Todd, i've always been a palomar guy and overall it is probably the best knot out there for most line, but not fluorocarbon. When using a palomar knot with fluorocarbon your only fishing 70 to 80% knot strength.I learned this from pro Aaron Martins, he told how many big tournaments he blowed by breaking off fluorocarbon with a palomar, especially drop shotting. Martins prefers the uni-not with fluorocarbon because your getting near 100% knot strength.You can perform this test yourself and it will prove true. Again i'll say the palomar may still be the best knot with other lines. ps: Berkley 100% fluorocarbon is one of the best going.Hope this helps, good luck